Associate Principal Scientist, DMPK

About the Role

As an Associate Principal Scientist specializing in Drug Metabolism and Pharmacokinetics (DMPK) at Bicycle Therapeutics, you will lead critical projects in drug discovery. Your expertise will drive the development of innovative bicyclic peptide therapeutics, coordinating experiments and collaborating with cross-functional teams to ensure timely and high-quality data delivery.

Responsibilities

• Coordinate DMPK experiments with CROs, managing budgets effectively.
• Design screening cascades to optimize pharmacokinetic properties.
• Review and report DMPK data for drug discovery projects.
• Integrate data to inform bicyclic peptide distribution and metabolism.
• Present findings at multifunctional project team meetings.

Requirements

• Industry experience in drug metabolism or pharmacology.
• In-depth understanding of DMPK science and ADME assays.
• Experience in pharmacokinetic data analysis software.
• Excellent organizational and communication skills.
• Hands-on experience in drug discovery projects.

Benefits

• Flexible working environment with a state-of-the-art campus.
• 28 days annual leave plus bank holidays.
• Employer pension contributions without employee input.
• Private medical insurance, including dental and optical.
• Access to subsidized gym membership and wellness programs.

Compensation

Competitive salary with an annual company bonus and additional benefits to be discussed during the interview process.

Location & Schedule

Position based in Cambridge, UK, with flexible working options available.

How to Apply

Please submit your application through the Bicycle Therapeutics careers page.